• A Methodical Quantification of Needle Visibility and Echogenicity in Ultrasound Images 

      Van De Berg, Nick J; Sanchez-Margallo, Juan A.; van Dijke, Arjan P; Langø, Thomas; Van Den Dobbelsteen, John J (Journal article; Peer reviewed, 2019)
      During ultrasound-guided percutaneous interventions, needle localization can be a challenge. To increase needle visibility, enhancements of both the imaging methods and the needle surface properties have been investigated. ...
    • A multimodal image guiding system for Navigated Ultrasound Bronchoscopy (EBUS): A human feasibility study 

      Sorger, Hanne; Hofstad, Erlend Fagertun; Amundsen, Tore; Langø, Thomas; Bakeng, Janne Beate Lervik; Leira, Håkon Olav (Journal article; Peer reviewed, 2017)
      Background Endobronchial ultrasound transbronchial needle aspiration (EBUS-TBNA) is the endoscopic method of choice for confirming lung cancer metastasis to mediastinal lymph nodes. Precision is crucial for correct ...
    • A new procedure for automatic path planning in bronchoscopy 

      Ciobirca, C; Langø, Thomas; Gruionu, G; Leira, Håkon Olav; Gruionu, Lucian; Pastrama, SD (Journal article; Peer reviewed, 2018)
      Virtual bronchoscopy is often used for planning a real bronchoscopy procedure. Software applications are developed for virtual bronchoscopy, involving usually segmentation of the tracheobronchial tree from the medical image ...
    • Accuracy of electromagnetic tracking with a prototype field generator in an interventional OR setting 

      Bø, Lars Eirik; Leira, Håkon Olav; Tangen, Geir Arne; Hofstad, Erlend Fagertun; Amundsen, Tore; Langø, Thomas (Journal article; Peer reviewed, 2012)
      Purpose: The authors have studied the accuracy and robustness of a prototype electromagnetic window field generator (WFG) in an interventional radiology suite with a robotic C-arm. The overall purpose is the development ...
    • Airway segmentation and centerline extraction from thoracic CT - Comparison of a new method to state of the art commercialized methods 

      Reynisson, Pall Jens; Scali, Marta; Smistad, Erik; Hofstad, Erlend Fagertun; Leira, Håkon Olav; Lindseth, Frank; Hernes, Toril A. Nagelhus; Amundsen, Tore; Sorger, Hanne; Langø, Thomas (Journal article; Peer reviewed, 2015)
      Introduction Our motivation is increased bronchoscopic diagnostic yield and optimized preparation, for navigated bronchoscopy. In navigated bronchoscopy, virtual 3D airway visualization is often used to guide a bronchoscopic ...
    • Anthropomorphic liver phantom with flow for multimodal image-guided liver therapy research and training 

      Rethy, Anna; Sæternes, Jørn Ove; Halgunset, Jostein; Mårvik, Ronald; Hofstad, Erlend Fagertun; Sanchez-Margallo, Juan A.; Langø, Thomas (Journal article; Peer reviewed, 2017)
      Purpose The objective of this study was to develop a multimodal, permanent liver phantom displaying functional vasculature and common pathologies, for teaching, training and equipment development in laparoscopic ultrasound ...
    • Aspiration and altered airway anatomy: a presentation with a twist 

      Cullivan, Sarah; Langø, Thomas; Cantillon-Murphy, Pádraig; Kennedy, Marcus P (Journal article; Peer reviewed, 2018)
      A 60-year-old woman presented to our hospital with severe hypercapnic respiratory failure in the absence of a prior smoking history. She reported a 1-day history of increased dyspnoea and a cough productive of green sputum. ...
    • Assessment and comparison of target registration accuracy in surgical instrument tracking technologies 

      Teatini, Andrea; Perez de Frutos, Javier; Langø, Thomas; Edwin, Bjørn; Elle, Ole Jacob (Journal article; Peer reviewed, 2018)
      Image guided surgery systems aim to support surgeons by providing reliable pre-operative and intra-operative imaging of the patient combined with the corresponding tracked instrument location. The image guidance is based ...
    • Block-matching-based registration to evaluate ultrasound visibility of percutaneous needles in liver-mimicking phantoms 

      Sánchez-Margallo, Juan A.; Tas, Lisette; Moelker, Adriaan; van den Dobbelsteen, John J.; Sánchez-Margallo, Francisco M.; Langø, Thomas; van Walsum, Theo; van de Berg, Nick J. (Peer reviewed; Journal article, 2021)
      Purpose: To present a novel methodical approach to compare visibility of percutaneous needles in ultrasound images. Methods: A motor-driven rotation platform was used to gradually change the needle angle while capturing ...
    • Can a Dinosaur Think? Implementation of Artificial Intelligence in Extracorporeal Shock Wave Lithotripsy 

      Muller, Sebastien; Abildsnes, Håkon; Østvik, Andreas; Kragset, Oda; Gangås, Inger Sofie Hovd; Birke, Harriet; Langø, Thomas; Arum, Carl-Jørgen (Peer reviewed; Journal article, 2021)
      Background: Extracorporeal shock wave lithotripsy (ESWL) of kidney stones is losing ground to more expensive and invasive endoscopic treatments. Objective: This proof-of-concept project was initiated to develop ...
    • Deep learning for image-based liver analysis — A comprehensive review focusing on malignant lesions 

      Survarachakan, Shanmugapriya; Prasad, Pravda Jith Ray; Naseem, Rabia; Perez de Frutos, Javier; Kumar, Rahul Prasanna; Langø, Thomas; Alaya Cheikh, Faouzi; Elle, Ole Jakob; Lindseth, Frank (Peer reviewed; Journal article, 2022)
      Deep learning-based methods, in particular, convolutional neural networks and fully convolutional networks are now widely used in the medical image analysis domain. The scope of this review focuses on the analysis using ...
    • Intraoperative localized constrained registration in navigated bronchoscopy 

      Hofstad, Erlend Fagertun; Sorger, Hanne; Bakeng, Janne Beate Lervik; Gruionu, Lucian; Leira, Håkon Olav; Amundsen, Tore; Langø, Thomas (Journal article; Peer reviewed, 2017)
      Purpose One of the major challenges in electromagnetic navigated bronchoscopy is the navigation accuracy. An initial rigid image-to-patient registration may not be optimal for the entire lung volume, as the lung tissue ...
    • Laboratory test of Single Landmark registration method for ultrasound-based navigation in laparoscopy using an open-source platform 

      Perez de Frutos, Javier; Hofstad, Erlend Fagertun; Solberg, Ole Vegard; Tangen, Geir Arne; Lindseth, Frank; Langø, Thomas; Elle, Ole Jacob; Mårvik, Ronald (Journal article; Peer reviewed, 2018)
      Purpose Test the feasibility of the novel Single Landmark image-to-patient registration method for use in the operating room for future clinical trials. The algorithm is implemented in the open-source platform CustusX, a ...
    • Lack of transfer of skills after virtual reality simulator training with haptic feedback 

      Våpenstad, Cecilie; Hofstad, Erlend Fagertun; Bø, Lars Eirik; Kuhry, Esther; Johnsen, Gjermund; Mårvik, Ronald; Langø, Thomas; Hernes, Toril A. Nagelhus (Journal article; Peer reviewed, 2017)
    • Learning deep abdominal CT registration through adaptive loss weighting and synthetic data generation 

      Perez de Frutos, Javier; Pedersen, Andre; Pelanis, Egidijus; Bouget, David Nicolas Jean-Mar; Survarachakan, Shanmugapriya; Langø, Thomas; Elle, Ole Jakob; Lindseth, Frank (Peer reviewed; Journal article, 2023)
      Purpose: This study aims to explore training strategies to improve convolutional neural network-based image-to-image deformable registration for abdominal imaging. Methods: Different training strategies, loss functions, ...
    • Mediastinal lymph nodes segmentation using 3D convolutional neural network ensembles and anatomical priors guiding 

      Bouget, David Nicolas Jean-Mar; Pedersen, André; Vanel, Johanna; Leira, Håkon Olav; Langø, Thomas (Peer reviewed; Journal article, 2022)
      As lung cancer evolves, the presence of potentially malignant lymph nodes must be assessed to properly estimate disease progression and select the best treatment strategy. A method for accurate and automatic segmentation ...
    • Multimodal Phantom of Liver Tissue 

      Chmarra, Magdalena Karolina; Hansen, Rune; Mårvik, Ronald; Langø, Thomas (Journal article, 2013)
      Medical imaging plays an important role in patients' care and is continuously being used in managing health and disease. To obtain the maximum benefit from this rapidly developing technology, further research is needed. ...
    • Navigated retrograde endoscopic myotomy (REM) for the treatment of therapy-resistant achalasia 

      Pham, Khanh Do-Cong; Havre, Roald Flesland; Langø, Thomas; Hofstad, Erlend Fagertun; Tangen, Geir Arne; Mårvik, Ronald; Pham, T.; Gilja, Odd Helge; Hatlebakk, Jan Gunnar; Viste, Asgaut (Journal article; Peer reviewed, 2018)
      Background In achalasia, muscle spasm may involve the proximal esophagus. When the muscle spasm is located in the proximal esophagus, conventional per oral endoscopic myotomy (POEM) may not be sufficient to relieve symptoms. ...
    • A novel clip-on device for electromagnetic tracking in endobronchial ultrasound bronchoscopy 

      Kildahl-Andersen, Arne; Hofstad, Erlend Fagertun; Peters, Karlijn; Van Beek, Gregory; Sorger, Hanne; Amundsen, Tore; Langø, Thomas; Leira, Håkon Olav (Peer reviewed; Journal article, 2022)
      Introduction: The established method for assessment of mediastinal and hilar lymph nodes is endobronchial ultrasound bronchoscopy (EBUS) with needle aspirations. Previously, we presented an electromagnetic navigation ...
    • Operating Room of the Future (FOR) Digital Healthcare Transformation in the Age of Artificial Intelligence 

      Trocin, Cristina; Skogås, Jan Gunnar; Langø, Thomas; Kiss, Gabriel Hanssen (Chapter, 2022)
      New technologies are emerging under the umbrella of digital transformation in healthcare such as artificial intelligence (AI) and medical analytics to provide insights beyond the abilities of human experts. Because AI is ...